Version 5.4
Homo sapiens Gene: NGDN
Summary
InnateDB Gene IDBG-3334.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NGDN
Gene Name neuroguidin, EIF4E binding protein
Synonyms C14orf120; CANu1; LCP5; lpd-2; NGD
Species Homo sapiens
Ensembl Gene ENSG00000129460
Encoded Proteins
IDBP-235965
neuroguidin, EIF4E binding protein
IDBP-292719
neuroguidin, EIF4E binding protein
IDBP-585406
neuroguidin, EIF4E binding protein
IDBP-595908
neuroguidin, EIF4E binding protein
IDBP-595836
neuroguidin, EIF4E binding protein
IDBP-583912
neuroguidin, EIF4E binding protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Neuroguidin is an EIF4E (MIM 133440)-binding protein that interacts with CPEB (MIM 607342) and functions as a translational regulatory protein during development of the vertebrate nervous system (Jung et al., 2006 [PubMed 16705177]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:23469688-23509862
Strand Forward strand
Band q11.2
Transcripts
ENST00000397154 ENSP00000380340
ENST00000408901 ENSP00000386134
ENST00000556378
ENST00000557097
ENST00000553336
ENST00000553439
ENST00000555128 ENSP00000451779
ENST00000556953
ENST00000556483 ENSP00000450659
ENST00000556022
ENST00000556580 ENSP00000452608
ENST00000556103
ENST00000556699 ENSP00000451942
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006417 regulation of translation
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0030175 filopodium
GO:0030424 axon
GO:0030425 dendrite
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022204
View Gene Order
ENSBTAG00000009595
Not yet available
Cross-References
SwissProt
TrEMBL H0YJQ1
UniProt Splice Variant
Entrez Gene 25983
UniGene Hs.630479
RefSeq NM_001042635 NM_015514
HUGO HGNC:20271
OMIM 610777
CCDS CCDS32051 CCDS41926
HPRD
IMGT
EMBL AL132855
GenPept
RNA Seq Atlas 25983

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca