InnateDB Protein
|
IDBP-292719.4
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
NGDN
|
Protein Name
|
neuroguidin, EIF4E binding protein
|
Synonyms
|
C14orf120; CANu1; LCP5; lpd-2; NGD;
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000386134
|
InnateDB Gene
|
IDBG-3334 (NGDN)
|
Protein Structure
|
|
Function |
Involved in the translational repression of cytoplasmic polyadenylation element (CPE)-containing mRNAs. {ECO:0000250}.
|
Subcellular Localization |
Nucleus {ECO:0000250}. Nucleus, nucleolus {ECO:0000269PubMed:18547334}. Chromosome, centromere {ECO:0000269PubMed:18547334}. Cytoplasm {ECO:0000250}. Cell projection, axon {ECO:0000250}. Cell projection, dendrite {ECO:0000250}. Cell projection, filopodium {ECO:0000250}. Note=Detected in axons, dendrites and filopodia. Colocalized with EIF4E in neurites (By similarity). Translocated from nucleolus to nuclear foci in response to UV damage. {ECO:0000250}.
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
4
[view]
|
Protein-Protein |
4
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
|
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR007146
Sas10/Utp3/C1D
|
PFAM |
PF04000
|
PRINTS |
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q8NEJ9
|
PhosphoSite |
PhosphoSite-Q8NEJ9
|
TrEMBL |
G3V601
|
UniProt Splice Variant |
|
Entrez Gene |
25983
|
UniGene |
Hs.630479
|
RefSeq |
NP_001036100
|
HUGO |
HGNC:20271
|
OMIM |
610777
|
CCDS |
CCDS41926
|
HPRD |
|
IMGT |
|
EMBL |
AK291875
AL050003
AL132855
BC030817
CH471078
|
GenPept |
AAH30817
BAF84564
CAB43232
EAW66149
|
|
|