Version 5.4
Bos taurus Gene: YES1
Summary
InnateDB Gene IDBG-644136.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol YES1
Gene Name tyrosine-protein kinase Yes
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000001523
Encoded Proteins
IDBP-696750
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000176105:
This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 24:35973659-36038238
Strand Reverse strand
Band
Transcripts
ENSBTAT00000001995 ENSBTAP00000001995
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 56 interaction(s) predicted by orthology.
Predicted by orthology
Total 56 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016740 transferase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0019899 enzyme binding
GO:0044325 ion channel binding
Biological Process
GO:0006468 protein phosphorylation
GO:0015758 glucose transport
GO:0016310 phosphorylation
GO:0018108 peptidyl-tyrosine phosphorylation
Cellular Component
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000176105
View Gene Order
ENSMUSG00000014932
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_1
Alpha6Beta4Integrin pathway
NetPath_6
KitReceptor pathway
NetPath_8
Wnt pathway
NetPath_24
TSLP pathway
NetPath_147
IL11 pathway
REACTOME
REACT_160274
FCGR activation pathway
REACT_23787
Regulation of signaling by CBL pathway
REACT_23837
Interleukin-3, 5 and GM-CSF signaling pathway
REACT_19405
CTLA4 inhibitory signaling pathway
REACT_19183
CD28 co-stimulation pathway
REACT_19344
Costimulation by the CD28 family pathway
REACT_12519
PECAM1 interactions pathway
REACT_12051
Cell surface interactions at the vascular wall pathway
REACT_115755
Signaling by ERBB2 pathway
REACT_111225
Regulation of KIT signaling pathway
REACT_111040
Signaling by SCF-KIT pathway
REACT_111045
Developmental Biology pathway
REACT_228085
EPHB-mediated forward signaling pathway
REACT_75790
Cytokine Signaling in Immune system pathway
REACT_6802
Innate Immune System pathway
REACT_18266
Axon guidance pathway
REACT_111102
Signal Transduction pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_228063
EPHA-mediated growth cone collapse pathway
REACT_22232
Signaling by Interleukins pathway
REACT_160123
Fcgamma receptor (FCGR) dependent phagocytosis pathway
REACT_228189
EPH-ephrin mediated repulsion of cells pathway
REACT_228170
EPH-Ephrin signaling pathway
REACT_604
Hemostasis pathway
REACT_239142
Innate Immune System pathway
REACT_227425
Regulation of KIT signaling pathway
REACT_188578
Signaling by SCF-KIT pathway
REACT_243939
EPHA-mediated growth cone collapse pathway
REACT_230745
Immune System pathway
REACT_196487
FCGR activation pathway
REACT_243590
EPH-ephrin mediated repulsion of cells pathway
REACT_258158
EPH-Ephrin signaling pathway
REACT_204081
CD28 co-stimulation pathway
REACT_225477
Costimulation by the CD28 family pathway
REACT_257656
EPHB-mediated forward signaling pathway
REACT_261444
Axon guidance pathway
REACT_209368
Fcgamma receptor (FCGR) dependent phagocytosis pathway
REACT_261568
CTLA4 inhibitory signaling pathway
REACT_229531
Adaptive Immune System pathway
REACT_188576
Developmental Biology pathway
REACT_188257
Signal Transduction pathway
KEGG
hsa04520
Adherens junction pathway
hsa04530
Tight junction pathway
mmu04530
Tight junction pathway
mmu04520
Adherens junction pathway
INOH
PID NCI
wnt_noncanonical_pathway
Noncanonical Wnt signaling pathway
Cross-References
SwissProt
TrEMBL A7MB57
UniProt Splice Variant
Entrez Gene 507632
UniGene Bt.33876
RefSeq NM_001101060
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC151348 DAAA02056661 DAAA02056662
GenPept AAI51349
RNA Seq Atlas 507632

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca