Mus musculus Gene: Yes1
Summary
InnateDB Gene IDBG-151540.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Yes1
Gene Name Yamaguchi sarcoma viral (v-yes) oncogene homolog 1
Synonyms p61-Yes; Yes;
Species Mus musculus
Ensembl Gene ENSMUSG00000014932
Encoded Proteins
Yamaguchi sarcoma viral (v-yes) oncogene homolog 1
Yamaguchi sarcoma viral (v-yes) oncogene homolog 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000176105:
This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:32611171-32687066
Strand Forward strand
Band B1
Transcripts
ENSMUST00000072311 ENSMUSP00000072154
ENSMUST00000168707 ENSMUSP00000132161
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 55 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 55 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005154 epidermal growth factor receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0019899 enzyme binding
GO:0044325 ion channel binding
Biological Process
GO:0006468 protein phosphorylation
GO:0015758 glucose transport
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0046777 protein autophosphorylation
Cellular Component
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005815 microtubule organizing center
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Innate Immune System pathway
Regulation of KIT signaling pathway
Signaling by SCF-KIT pathway
EPHA-mediated growth cone collapse pathway
Immune System pathway
FCGR activation pathway
EPH-ephrin mediated repulsion of cells pathway
EPH-Ephrin signaling pathway
CD28 co-stimulation pathway
Costimulation by the CD28 family pathway
EPHB-mediated forward signaling pathway
Axon guidance pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
CTLA4 inhibitory signaling pathway
Adaptive Immune System pathway
Developmental Biology pathway
Signal Transduction pathway
KEGG
Adherens junction pathway
Tight junction pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
Alpha6Beta4Integrin pathway
KitReceptor pathway
Wnt pathway
TSLP pathway
IL11 pathway
REACTOME
Developmental Biology pathway
FCGR activation pathway
PECAM1 interactions pathway
EPHB-mediated forward signaling pathway
Interleukin-3, 5 and GM-CSF signaling pathway
Cytokine Signaling in Immune system pathway
Innate Immune System pathway
Signaling by SCF-KIT pathway
Axon guidance pathway
Signal Transduction pathway
CD28 co-stimulation pathway
Adaptive Immune System pathway
Immune System pathway
EPHA-mediated growth cone collapse pathway
Signaling by Interleukins pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
EPH-ephrin mediated repulsion of cells pathway
EPH-Ephrin signaling pathway
Signaling by ERBB2 pathway
Regulation of KIT signaling pathway
Costimulation by the CD28 family pathway
CTLA4 inhibitory signaling pathway
Cell surface interactions at the vascular wall pathway
Hemostasis pathway
Regulation of signaling by CBL pathway
KEGG
Adherens junction pathway
Tight junction pathway
INOH
PID BIOCARTA
PID NCI
Noncanonical Wnt signaling pathway
Cross-References
SwissProt Q04736
TrEMBL Q3TJI7 Q8C6U9
UniProt Splice Variant
Entrez Gene 22612
UniGene Mm.395218
RefSeq NM_009535 NM_001205132 NM_001205133
OMIM
CCDS CCDS39061
HPRD
IMGT
MGI ID MGI:99147
MGI Symbol Yes1
EMBL AK053141 AK167420 BC010594 CH466524 L25762 X67677
GenPept AAA40020 AAH10594 BAC35280 BAE39508 CAA47909 EDL37394
RNA Seq Atlas 22612