Version 5.4
Mus musculus Gene: Edc3
Summary
InnateDB Gene IDBG-170800.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Edc3
Gene Name enhancer of mRNA decapping 3 homolog (S. cerevisiae)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000038957
Encoded Proteins
IDBP-170802
enhancer of mRNA decapping 3 homolog (S. cerevisiae)
IDBP-538424
enhancer of mRNA decapping 3 homolog (S. cerevisiae)
IDBP-540152
enhancer of mRNA decapping 3 homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000179151:
EDC3 is associated with an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005 [PubMed 16364915]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:57708540-57752499
Strand Forward strand
Band B
Transcripts
ENSMUST00000043990 ENSMUSP00000049146
ENSMUST00000137245 ENSMUSP00000123317
ENSMUST00000142807 ENSMUSP00000123505
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0000932 cytoplasmic mRNA processing body
GO:0005575 cellular_component
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000179151
View Gene Order
ENSBTAG00000007308
Not yet available
Pathways
NETPATH
REACTOME
REACT_261877
mRNA decay by 5' to 3' exoribonuclease pathway
REACT_233572
Gene Expression pathway
REACT_235784
Deadenylation-dependent mRNA decay pathway
KEGG
mmu03018
RNA degradation pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_20518
mRNA decay by 5' to 3' exoribonuclease pathway
REACT_20639
Deadenylation-dependent mRNA decay pathway
REACT_71
Gene Expression pathway
KEGG
hsa03018
RNA degradation pathway
INOH
PID NCI
Cross-References
SwissProt Q8K2D3
TrEMBL A0ELI5 D3YYS4
UniProt Splice Variant
Entrez Gene 353190
UniGene Mm.268104 Mm.412903 Mm.412992
RefSeq NM_153799 XM_006511247
OMIM
CCDS CCDS23231
HPRD
IMGT
MGI ID MGI:2142951
MGI Symbol Edc3
EMBL AC122515 AK146804 AK166286 AK168118 BC031725 BC033484 DQ240818 DQ240819
GenPept AAH31725 AAH33484 ABB72679 ABB72680 BAE27445 BAE38683 BAE40089
RNA Seq Atlas 353190

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca