InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Edc3

Summary

InnateDB Protein

IDBP-170802.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Edc3

Protein Name

enhancer of mRNA decapping 3 homolog (S. cerevisiae)

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000049146

InnateDB Gene

IDBG-170800 (Edc3)

Protein Structure

UniProt Annotation

Function

Binds single-stranded RNA. In the process of mRNA degradation, may play a role in mRNA decapping (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasm, P-body {ECO:0000250}. Note=Processing bodies (PB). {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	14 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0042802	identical protein binding

Biological Process

GO:0008150

biological_process

Cellular Component

GO:0000932	cytoplasmic mRNA processing body
GO:0005575	cellular_component
GO:0016020	membrane

Protein Structure and Domains

PDB ID

MGI:2142951

InterPro

IPR004443 YjeF N-terminal domain
IPR019050 FDF domain

PFAM

PF03853
PF09532

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8K2D3

PhosphoSite

PhosphoSite-Q8K2D3

TrEMBL

D3YYS4

UniProt Splice Variant

Entrez Gene

353190

UniGene

Mm.412992

RefSeq

NP_722494

MGI ID

MGI Symbol

Edc3

OMIM

CCDS

CCDS23231

HPRD

IMGT

EMBL

AC122515 AK146804 AK166286 AK168118 BC031725 BC033484 DQ240818 DQ240819

GenPept

AAH31725 AAH33484 ABB72679 ABB72680 BAE27445 BAE38683 BAE40089