Mus musculus Gene: Mfng | |||||||||||
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Summary | |||||||||||
InnateDB Gene | IDBG-159753.6 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | Mfng | ||||||||||
Gene Name | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | ||||||||||
Synonyms | AW546563 | ||||||||||
Species | Mus musculus | ||||||||||
Ensembl Gene | ENSMUSG00000018169 | ||||||||||
Encoded Proteins |
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
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Protein Structure | |||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
Entrez Gene | |||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100060:
This gene is a member of the fringe gene family which also includes radical and lunatic fringe genes. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. [provided by RefSeq, Oct 2009] |
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Gene Information | |||||||||||
Type | Protein coding | ||||||||||
Genomic Location | Chromosome 15:78755882-78773475 | ||||||||||
Strand | Reverse strand | ||||||||||
Band | E1 | ||||||||||
Transcripts |
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Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||
NETPATH | |||||||||||
REACTOME |
Pre-NOTCH Expression and Processing pathway
Pre-NOTCH Processing in Golgi pathway
Signal Transduction pathway
Signaling by NOTCH pathway
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KEGG |
Notch signaling pathway pathway
Other types of O-glycan biosynthesis pathway
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INOH | |||||||||||
PID NCI | |||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||
NETPATH |
Notch pathway
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REACTOME |
Pre-NOTCH Processing in Golgi pathway
Pre-NOTCH Expression and Processing pathway
Signal Transduction pathway
Signaling by NOTCH pathway
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KEGG |
Notch signaling pathway pathway
Other types of O-glycan biosynthesis pathway
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INOH | |||||||||||
PID NCI | |||||||||||
Cross-References | |||||||||||
SwissProt | |||||||||||
TrEMBL | |||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | |||||||||||
UniGene | Mm.149235 | ||||||||||
RefSeq | NM_008595 XM_006520551 XM_006520552 | ||||||||||
OMIM | |||||||||||
CCDS | CCDS27622 | ||||||||||
HPRD | |||||||||||
IMGT | |||||||||||
MGI ID | |||||||||||
MGI Symbol | |||||||||||
EMBL | |||||||||||
GenPept | |||||||||||
RNA Seq Atlas | |||||||||||