InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: CLDN3

Summary

InnateDB Protein

IDBP-701438.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CLDN3

Protein Name

Claudin-3

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000001810

InnateDB Gene

IDBG-648721 (CLDN3)

Protein Structure

UniProt Annotation

Function

Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. {ECO:0000250}.

Subcellular Localization

Cell junction, tight junction {ECO:0000250}. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005198	structural molecule activity
GO:0005515	protein binding
GO:0042802	identical protein binding

Biological Process

GO:0001666	response to hypoxia
GO:0016338	calcium-independent cell-cell adhesion

Cellular Component

GO:0005886	plasma membrane
GO:0005923	tight junction
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0016328	lateral plasma membrane
GO:0030054	cell junction
GO:0070062	extracellular vesicular exosome