InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: UBE2E1

Summary

InnateDB Protein

IDBP-367660.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

UBE2E1

Protein Name

ubiquitin-conjugating enzyme E2E 1

Synonyms

UBCH6;

Species

Homo sapiens

Ensembl Protein

ENSP00000411351

InnateDB Gene

IDBG-22029 (UBE2E1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 119 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	119 [view]
Protein-Protein	119 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004842	ubiquitin-protein transferase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0042296	ISG15 ligase activity

Biological Process

GO:0000209	protein polyubiquitination
GO:0000278	mitotic cell cycle
GO:0006511	ubiquitin-dependent protein catabolic process
GO:0007094	mitotic spindle assembly checkpoint
GO:0010390	histone monoubiquitination
GO:0016567	protein ubiquitination
GO:0019221	cytokine-mediated signaling pathway
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0032020	ISG15-protein conjugation
GO:0033523	histone H2B ubiquitination
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0070936	protein K48-linked ubiquitination