InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cnn2

Summary

InnateDB Protein

IDBP-271013.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Cnn2

Protein Name

calponin 2

Synonyms

AA408047; AI324678; Calpo2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000101013

InnateDB Gene

IDBG-171955 (Cnn2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0005515	protein binding

Biological Process

GO:0010628	positive regulation of gene expression
GO:0030097	hemopoiesis
GO:0030336	negative regulation of cell migration
GO:0031032	actomyosin structure organization
GO:0032970	regulation of actin filament-based process
GO:0042060	wound healing
GO:0042127	regulation of cell proliferation
GO:0050765	negative regulation of phagocytosis
GO:0071260	cellular response to mechanical stimulus

Cellular Component

GO:0001725

stress fiber

Protein Structure and Domains

PDB ID

MGI:105093

InterPro

IPR000557 Calponin repeat
IPR001715 Calponin homology domain
IPR001997 Calponin
IPR003096 Smooth muscle protein/calponin

PFAM

PF00402
PF00307

PRINTS

PR00889
PR00888

PIRSF

SMART

SM00033

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3Z7R6

UniProt Splice Variant

Entrez Gene

12798

UniGene

Mm.395408

RefSeq

MGI ID

MGI Symbol

Cnn2

OMIM

CCDS

HPRD

IMGT

EMBL

AC151846

GenPept