Version 5.4
Mus musculus Gene: Cnn2
Summary
InnateDB Gene IDBG-171955.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cnn2
Gene Name calponin 2
Synonyms AA408047; AI324678; Calpo2
Species Mus musculus
Ensembl Gene ENSMUSG00000004665
Encoded Proteins
IDBP-171957
calponin 2
IDBP-271013
calponin 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000064666:
The protein encoded by this gene, which can bind actin, calmodulin, troponin C, and tropomyosin, may function in the structural organization of actin filaments. The encoded protein could play a role in smooth muscle contraction and cell adhesion. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:79988584-79996062
Strand Forward strand
Band C1
Transcripts
ENSMUST00000004784 ENSMUSP00000004784
ENSMUST00000105374 ENSMUSP00000101013
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
GO:0005516 calmodulin binding
Biological Process
GO:0010628 positive regulation of gene expression
GO:0030097 hemopoiesis
GO:0030336 negative regulation of cell migration
GO:0031032 actomyosin structure organization
GO:0032970 regulation of actin filament-based process
GO:0042060 wound healing
GO:0042127 regulation of cell proliferation
GO:0050765 negative regulation of phagocytosis
GO:0071260 cellular response to mechanical stimulus
Cellular Component
GO:0001725 stress fiber
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000064666
View Gene Order
ENSBTAG00000020764
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.157770 Mm.395408
RefSeq NM_007725
OMIM
CCDS CCDS24003
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca