InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ranbp1

Summary

InnateDB Protein

IDBP-249179.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ranbp1

Protein Name

RAN binding protein 1

Synonyms

Htf9a;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000111309

InnateDB Gene

IDBG-141228 (Ranbp1)

Protein Structure

UniProt Annotation

Function

Inhibits GTP exchange on Ran. Forms a Ran-GTP-RANBP1 trimeric complex. Increase GTP hydrolysis induced by the Ran GTPase activating protein RANGAP1. May act in an intracellular signaling pathway which may control the progression through the cell cycle by regulating the transport of protein and nucleic acids across the nuclear membrane.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	24 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005096	GTPase activator activity

Biological Process

GO:0007051	spindle organization
GO:0043547	positive regulation of GTPase activity
GO:0046604	positive regulation of mitotic centrosome separation
GO:0046907	intracellular transport