Version 5.4
Mus musculus Protein: Mink1
Summary
InnateDB Protein IDBP-194771.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Mink1
Protein Name misshapen-like kinase 1 (zebrafish)
Synonyms B55; Map4k6; MINK; Ysk2;
Species Mus musculus
Ensembl Protein ENSMUSP00000078234
InnateDB Gene IDBG-194763 (Mink1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004702 receptor signaling protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005083 small GTPase regulator activity
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
GO:0023014 signal transduction by phosphorylation
GO:0045060 negative thymic T cell selection
GO:0050790 regulation of catalytic activity
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1355329
InterPro IPR000719 Protein kinase domain
IPR001180 Citron-like
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine- /dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR020635 Tyrosine-protein kinase, catalytic domain
PFAM PF00069
PF00780
PF07714
PRINTS PR00109
PIRSF
SMART SM00036
SM00220
SM00219
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q8K4S8
UniProt Splice Variant
Entrez Gene 50932
UniGene Mm.42967
RefSeq
MGI ID
MGI Symbol Mink1
OMIM
CCDS
HPRD
IMGT
EMBL AB070514 AL592547
GenPept BAB97285

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca