Version 5.4
Homo sapiens Gene: NUSAP1
Summary
InnateDB Gene IDBG-7026.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NUSAP1
Gene Name nucleolar and spindle associated protein 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000137804
Encoded Proteins
IDBP-7028
nucleolar and spindle associated protein 1
IDBP-366944
nucleolar and spindle associated protein 1
IDBP-366949
nucleolar and spindle associated protein 1
IDBP-600577
nucleolar and spindle associated protein 1
IDBP-598557
nucleolar and spindle associated protein 1
IDBP-588416
nucleolar and spindle associated protein 1
IDBP-590250
nucleolar and spindle associated protein 1
IDBP-603779
nucleolar and spindle associated protein 1
IDBP-597179
nucleolar and spindle associated protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary NUSAP1 is a nucleolar-spindle-associated protein that plays a role in spindle microtubule organization (Raemaekers et al., 2003 [PubMed 12963707]).[supplied by OMIM, Jun 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:41332694-41381050
Strand Forward strand
Band q15.1
Transcripts
ENST00000260359 ENSP00000260359
ENST00000414849 ENSP00000400746
ENST00000450592 ENSP00000401014
ENST00000558123
ENST00000559046 ENSP00000452725
ENST00000559596 ENSP00000453403
ENST00000558582
ENST00000560747 ENSP00000454097
ENST00000559659
ENST00000560177 ENSP00000453657
ENST00000557840 ENSP00000453428
ENST00000560898 ENSP00000453558
ENST00000560318
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 18 [view]
Protein-Protein 16 [view]
Protein-DNA 1 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0008017 microtubule binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000070 mitotic sister chromatid segregation
GO:0000281 mitotic cytokinesis
GO:0007076 mitotic chromosome condensation
GO:0040001 establishment of mitotic spindle localization
GO:0045840 positive regulation of mitosis
Cellular Component
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005819 spindle
GO:0005874 microtubule
GO:0005876 spindle microtubule
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000027306
View Gene Order
ENSBTAG00000010774
Not yet available
Cross-References
SwissProt Q9BXS6
TrEMBL E9PB35
UniProt Splice Variant
Entrez Gene 51203
UniGene Hs.603916 Hs.615092
RefSeq NM_001243144 NM_001243142 NM_001243143 NM_001301136 NM_016359 NM_018454 XM_005254428 XM_005254429 XM_005254430 XM_006720559 XM_006720560 XM_006720561
HUGO HGNC:18538
OMIM 612818
CCDS CCDS58358 CCDS45234 CCDS45236 CCDS58356 CCDS58357 CCDS73708
HPRD
IMGT
EMBL AC087721 AF090915 AF217513 AF290612 AF305711 AK023483 AK222819 AK293168 AL833611 BC001308 BC010838 BC012887 BC024772 CH471125
GenPept AAF24034 AAF67624 AAG25874 AAH01308 AAH10838 AAH12887 AAH24772 AAK28023 BAB14586 BAD96539 BAG56712 EAW92483 EAW92486
RNA Seq Atlas 51203

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca