Homo sapiens Gene: ZDHHC8
Summary
InnateDB Gene IDBG-1624.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZDHHC8
Gene Name zinc finger, DHHC-type containing 8
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000099904
Encoded Proteins
zinc finger, DHHC-type containing 8
zinc finger, DHHC-type containing 8
zinc finger, DHHC-type containing 8
zinc finger, DHHC-type containing 8
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a four transmembrane protein that is a member of the zinc finger DHHC domain-containing protein family. The encoded protein may function as a palmitoyltransferase. Defects in this gene may be associated with a susceptibility to schizophrenia. Alternate splicing of this gene results in multiple transcript variants. A pseudogene of this gene is found on chromosome 22.[provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:20129456-20148007
Strand Forward strand
Band q11.21
Transcripts
ENST00000320602 ENSP00000317804
ENST00000334554 ENSP00000334490
ENST00000405930 ENSP00000384716
ENST00000436518 ENSP00000412807
ENST00000468112
ENST00000469212
ENST00000472497
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016409 palmitoyltransferase activity
GO:0019706 protein-cysteine S-palmitoyltransferase activity
Biological Process
GO:0007275 multicellular organismal development
GO:0007626 locomotory behavior
GO:0008152 metabolic process
GO:0018345 protein palmitoylation
Cellular Component
GO:0005739 mitochondrion
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030659 cytoplasmic vesicle membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Cross-References
SwissProt
TrEMBL C9JVM2
UniProt Splice Variant
Entrez Gene 29801
UniGene Hs.625140 Hs.63128
RefSeq NM_001185024 NM_013373 XM_006724239
HUGO HGNC:18474
OMIM 608784
CCDS CCDS13776 CCDS54502
HPRD 12298
IMGT
EMBL AC006547
GenPept
RNA Seq Atlas 29801