Version 5.4
Homo sapiens Protein: ZDHHC8
Summary
InnateDB Protein IDBP-292561.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZDHHC8
Protein Name zinc finger, DHHC-type containing 8
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000384716
InnateDB Gene IDBG-1624 (ZDHHC8)
Protein Structure
UniProt Annotation
Function Palmitoyltransferase involved in glutamatergic transmission. Mediates palmitoylation of ABCA1. {ECO:0000269PubMed:19556522}.
Subcellular Localization Cytoplasmic vesicle membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016409 palmitoyltransferase activity
GO:0019706 protein-cysteine S-palmitoyltransferase activity
Biological Process
GO:0007275 multicellular organismal development
GO:0007626 locomotory behavior
GO:0018345 protein palmitoylation
Cellular Component
GO:0005739 mitochondrion
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030659 cytoplasmic vesicle membrane
Protein Structure and Domains
PDB ID
InterPro IPR001594 Zinc finger, DHHC-type, palmitoyltransferase
IPR016201 Plexin-like fold
PFAM PF01529
PRINTS
PIRSF
SMART SM00423
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9ULC8
PhosphoSite PhosphoSite-Q9ULC8
TrEMBL
UniProt Splice Variant
Entrez Gene 29801
UniGene Hs.63128
RefSeq NP_001171953
HUGO HGNC:18474
OMIM 608784
CCDS CCDS54502
HPRD 12298
IMGT
EMBL AB033118 AC006547 AK131238 AY894890 BC053544 CH471176 CR456357
GenPept AAH53544 AAX73369 BAA86606 BAD18420 CAG30243 EAX02984

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca