Version 5.4
Homo sapiens Gene: GPR65
Summary
InnateDB Gene IDBG-14840.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GPR65
Gene Name G protein-coupled receptor 65
Synonyms hTDAG8; TDAG8
Species Homo sapiens
Ensembl Gene ENSG00000140030
Encoded Proteins
IDBP-14842
G protein-coupled receptor 65
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 14:88005124-88014811
Strand Forward strand
Band q31.3
Transcripts
ENST00000267549 ENSP00000267549
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0006915 apoptotic process
GO:0006955 immune response
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007275 multicellular organismal development
GO:0010447 response to acidity
GO:0030819 positive regulation of cAMP biosynthetic process
GO:0031532 actin cytoskeleton reorganization
GO:0032862 activation of Rho GTPase activity
GO:0051496 positive regulation of stress fiber assembly
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000021886
View Gene Order
ENSBTAG00000012737
Not yet available
Pathways
NETPATH
REACTOME
REACT_18283
G alpha (q) signalling events pathway
REACT_120966
Gastrin-CREB signalling pathway via PKC and MAPK pathway
REACT_14828
Class A/1 (Rhodopsin-like receptors) pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_21340
GPCR ligand binding pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8IYL9
TrEMBL B5B0C2
UniProt Splice Variant
Entrez Gene 8477
UniGene Hs.443243
RefSeq NM_003608
HUGO HGNC:4517
OMIM 604620
CCDS CCDS9879
HPRD
IMGT
EMBL AL157955 BC035633 BC071715 CH471061 EU883574 U95218
GenPept AAC31794 AAH35633 AAH71715 ACG60648 EAW81365
RNA Seq Atlas 8477

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca