Version 5.4
Mus musculus Gene: Gpr65
Summary
InnateDB Gene IDBG-162231.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gpr65
Gene Name G-protein coupled receptor 65
Synonyms Dig1; Gpcr25; TDAG8
Species Mus musculus
Ensembl Gene ENSMUSG00000021886
Encoded Proteins
IDBP-162233
G-protein coupled receptor 65
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000140030:
Gene Information
Type Protein coding
Genomic Location Chromosome 12:98268635-98276624
Strand Forward strand
Band E
Transcripts
ENSMUST00000075072 ENSMUSP00000074581
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0006915 apoptotic process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0010447 response to acidity
GO:0030819 positive regulation of cAMP biosynthetic process
GO:0031532 actin cytoskeleton reorganization
GO:0032862 activation of Rho GTPase activity
GO:0051496 positive regulation of stress fiber assembly
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000140030
View Gene Order
ENSBTAG00000012737
Not yet available
Pathways
NETPATH
REACTOME
REACT_223625
GPCR downstream signaling pathway
REACT_254215
Signaling by GPCR pathway
REACT_261161
Class A/1 (Rhodopsin-like receptors) pathway
REACT_188573
Gastrin-CREB signalling pathway via PKC and MAPK pathway
REACT_231468
GPCR ligand binding pathway
REACT_207651
G alpha (q) signalling events pathway
REACT_188257
Signal Transduction pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_18283
G alpha (q) signalling events pathway
REACT_120966
Gastrin-CREB signalling pathway via PKC and MAPK pathway
REACT_14828
Class A/1 (Rhodopsin-like receptors) pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_21340
GPCR ligand binding pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q61038
TrEMBL Q3UQ35
UniProt Splice Variant
Entrez Gene 14744
UniGene Mm.378924
RefSeq NM_008152
OMIM
CCDS CCDS26096
HPRD
IMGT
MGI ID MGI:108031
MGI Symbol Gpr65
EMBL AK142853 BC011332 U39827
GenPept AAB02188 AAH11332 BAE25209
RNA Seq Atlas 14744

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca