Bos taurus Gene: FKBP14
Summary
InnateDB Gene IDBG-633477.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FKBP14
Gene Name peptidyl-prolyl cis-trans isomerase FKBP14 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000007870
Encoded Proteins
FK506 binding protein 14, 22 kDa
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000106080:
The protein encoded by this gene is a member of the FK506-binding protein family of peptidyl-prolyl cis-trans isomerases. The encoded protein is found in the lumen of the endoplasmic reticulum, where it is thought to accelerate protein folding. Defects in this gene are a cause of a type of Ehlers-Danlos syndrome (EDS). Both a protein-coding variant and noncoding variants are transcribed from this gene. [provided by RefSeq, Mar 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:66758679-66770727
Strand Forward strand
Band
Transcripts
ENSBTAT00000033684 ENSBTAP00000033594
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
GO:0005509 calcium ion binding
GO:0005528 FK506 binding
Biological Process
GO:0000413 protein peptidyl-prolyl isomerization
GO:0006457 protein folding
GO:0061077 chaperone-mediated protein folding
Cellular Component
GO:0005789 endoplasmic reticulum membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
XBP1(S) activates chaperone genes pathway
IRE1alpha activates chaperones pathway
Unfolded Protein Response (UPR) pathway
Metabolism of proteins pathway
Unfolded Protein Response (UPR) pathway
Metabolism of proteins pathway
IRE1alpha activates chaperones pathway
XBP1(S) activates chaperone genes pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001076391
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas