Mus musculus Gene: Epha5 | |||||||||||||||||||||||||
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Summary | |||||||||||||||||||||||||
InnateDB Gene | IDBG-174718.6 | ||||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||||
Gene Symbol | Epha5 | ||||||||||||||||||||||||
Gene Name | Eph receptor A5 | ||||||||||||||||||||||||
Synonyms | AI854630; AW125296; bsk; Cek7; Ehk1; Els1; Hek7; Rek7 | ||||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000029245 | ||||||||||||||||||||||||
Encoded Proteins |
Eph receptor A5
Eph receptor A5
Eph receptor A5
Eph receptor A5
Eph receptor A5
Eph receptor A5
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Protein Structure | |||||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000145242:
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2009] This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Aug 2013] |
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Gene Information | |||||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||||
Genomic Location | Chromosome 5:84057791-84417382 | ||||||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||||||
Band | E1 | ||||||||||||||||||||||||
Transcripts | |||||||||||||||||||||||||
Interactions | |||||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||||
REACTOME |
EPHA-mediated growth cone collapse pathway
EPH-ephrin mediated repulsion of cells pathway
EPH-Ephrin signaling pathway
Axon guidance pathway
Developmental Biology pathway
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KEGG |
Axon guidance pathway
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INOH | |||||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||||
REACTOME |
Developmental Biology pathway
Axon guidance pathway
EPHA-mediated growth cone collapse pathway
EPH-ephrin mediated repulsion of cells pathway
EPH-Ephrin signaling pathway
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KEGG |
Axon guidance pathway
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INOH | |||||||||||||||||||||||||
PID NCI |
Ephrin A reverse signaling
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Cross-References | |||||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||||
TrEMBL | |||||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||||
UniGene | Mm.137991 | ||||||||||||||||||||||||
RefSeq | NM_007937 XM_006534769 XM_006534771 | ||||||||||||||||||||||||
OMIM | |||||||||||||||||||||||||
CCDS | CCDS19376 | ||||||||||||||||||||||||
HPRD | |||||||||||||||||||||||||
IMGT | |||||||||||||||||||||||||
MGI ID | |||||||||||||||||||||||||
MGI Symbol | |||||||||||||||||||||||||
EMBL | |||||||||||||||||||||||||
GenPept | |||||||||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||||||||