Version 5.4
Mus musculus Gene: Iqsec1
Summary
InnateDB Gene IDBG-169366.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Iqsec1
Gene Name IQ motif and Sec7 domain 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000034312
Encoded Proteins
IDBP-169374
IQ motif and Sec7 domain 1
IDBP-169376
IQ motif and Sec7 domain 1
IDBP-537900
IQ motif and Sec7 domain 1
IDBP-789510
IQ motif and Sec7 domain 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000144711:
Gene Information
Type Protein coding
Genomic Location Chromosome 6:90659598-90810123
Strand Reverse strand
Band D1
Transcripts
ENSMUST00000101153 ENSMUSP00000098712
ENSMUST00000101151 ENSMUSP00000098710
ENSMUST00000154198
ENSMUST00000141434
ENSMUST00000156834 ENSMUSP00000118802
ENSMUST00000133492
ENSMUST00000146977
ENSMUST00000189881 ENSMUSP00000140030
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005086 ARF guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
Biological Process
GO:0030036 actin cytoskeleton organization
GO:0032012 regulation of ARF protein signal transduction
GO:0043087 regulation of GTPase activity
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0030054 cell junction
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000144711
View Gene Order
ENSBTAG00000003237
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04144
Endocytosis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04144
Endocytosis pathway
INOH
PID NCI
plexind1_pathway
Plexin-D1 Signaling
arf6_pathway
Arf6 signaling events
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.196943
RefSeq NM_001134383 NM_001134384 XM_006505983 XM_006505984 XM_006505985 XM_006505986 XM_006505987 XM_006505988 XM_006505989 XM_006505990 XM_006505992 XM_006505993 XM_006505994
OMIM
CCDS CCDS51850 CCDS51851
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca