Mus musculus Gene: Ctdp1
Summary
InnateDB Gene IDBG-161408.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ctdp1
Gene Name CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
Synonyms 4930563P03Rik; AW553592
Species Mus musculus
Ensembl Gene ENSMUSG00000033323
Encoded Proteins
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000060069:
This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF, and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II), making it available for initiation of gene expression. Mutations in this gene are associated with congenital cataracts, facial dysmorphism and neuropathy syndrome (CCFDN). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:80407959-80469695
Strand Reverse strand
Band E3
Transcripts
ENSMUST00000036229 ENSMUSP00000038938
ENSMUST00000161003 ENSMUSP00000123705
ENSMUST00000160434
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 44 interaction(s) predicted by orthology.
Predicted by orthology
Total 44 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004721 phosphoprotein phosphatase activity
GO:0005515 protein binding
GO:0008420 CTD phosphatase activity
Biological Process
GO:0006470 protein dephosphorylation
GO:0010458 exit from mitosis
Cellular Component
GO:0000922 spindle pole
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005819 spindle
GO:0015629 actin cytoskeleton
GO:0030496 midbody
GO:0051233 spindle midzone
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
Formation of the Early Elongation Complex pathway
Formation of RNA Pol II elongation complex pathway
RNA Polymerase II Transcription Elongation pathway
RNA Polymerase II Pre-transcription Events pathway
Gene Expression pathway
RNA Polymerase II Transcription pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Tat-mediated HIV elongation arrest and recovery pathway
Pausing and recovery of Tat-mediated HIV elongation pathway
RNA Polymerase II Pre-transcription Events pathway
Formation of RNA Pol II elongation complex pathway
Formation of the Early Elongation Complex pathway
RNA Polymerase II Transcription Elongation pathway
Formation of HIV elongation complex in the absence of HIV Tat pathway
Pausing and recovery of HIV elongation pathway
Formation of the HIV-1 Early Elongation Complex pathway
Formation of HIV-1 elongation complex containing HIV-1 Tat pathway
Tat-mediated elongation of the HIV-1 transcript pathway
Abortive elongation of HIV-1 transcript in the absence of Tat pathway
HIV elongation arrest and recovery pathway
Transcription of the HIV genome pathway
Late Phase of HIV Life Cycle pathway
HIV Transcription Elongation pathway
RNA Polymerase II Transcription pathway
HIV Life Cycle pathway
HIV Infection pathway
Gene Expression pathway
Disease pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q7TSG2
TrEMBL
UniProt Splice Variant
Entrez Gene 67655
UniGene Mm.312893
RefSeq NM_026295
OMIM
CCDS CCDS29368
HPRD
IMGT
MGI ID MGI:1926953
MGI Symbol Ctdp1
EMBL AK016213 BC052934 BC053435
GenPept AAH52934 AAH53435 BAB30150
RNA Seq Atlas 67655