InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: BID

Summary

InnateDB Protein

IDBP-812719.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BID

Protein Name

BH3 interacting domain death agonist

Synonyms

FP497;

Species

Homo sapiens

Ensembl Protein

ENSP00000480414

InnateDB Gene

IDBG-1050 (BID)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 99 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	99 [view]
Protein-Protein	97 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005123	death receptor binding
GO:0005515	protein binding

Biological Process

GO:0001836	release of cytochrome c from mitochondria
GO:0006915	apoptotic process
GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors
GO:0008637	apoptotic mitochondrial changes
GO:0032461	positive regulation of protein oligomerization
GO:0032464	positive regulation of protein homooligomerization
GO:0042770	signal transduction in response to DNA damage
GO:0043065	positive regulation of apoptotic process
GO:0051402	neuron apoptotic process
GO:0090150	establishment of protein localization to membrane
GO:0090200	positive regulation of release of cytochrome c from mitochondria
GO:0097193	intrinsic apoptotic signaling pathway
GO:1900740	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
GO:2001238	positive regulation of extrinsic apoptotic signaling pathway
GO:2001244	positive regulation of intrinsic apoptotic signaling pathway

Cellular Component

GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005741	mitochondrial outer membrane
GO:0005829	cytosol
GO:0016020	membrane
GO:0070062	extracellular vesicular exosome