Version 5.4
Mus musculus Protein: C3
Summary
InnateDB Protein IDBP-713211.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol C3
Protein Name
Synonyms AI255234; ASP; HSE-MSF; Plp;
Species Mus musculus
Ensembl Protein ENSMUSP00000135663
InnateDB Gene IDBG-193788 (C3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Experimentally validated
Total 16 [view]
Protein-Protein 15 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 20 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001798 positive regulation of type IIa hypersensitivity
GO:0006956 complement activation
GO:0050766 positive regulation of phagocytosis
Cellular Component
Protein Structure and Domains
PDB ID MGI:88227
InterPro IPR008993 Tissue inhibitor of metalloproteinases-like, OB-fold
IPR011625 Alpha-2-macroglobulin, N-terminal 2
PFAM PF07703
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H3BL60
UniProt Splice Variant
Entrez Gene 12266
UniGene Mm.19131
RefSeq
MGI ID
MGI Symbol C3
OMIM
CCDS
HPRD
IMGT
EMBL CH466537 CT025692
GenPept EDL38246

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca