Version 5.4
Bos taurus Protein: BT.22013
Summary
InnateDB Protein IDBP-699587.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.22013
Protein Name protein kinase C eta type
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000004240
InnateDB Gene IDBG-646756 (BT.22013)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004697 protein kinase C activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016740 transferase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0017160 Ral GTPase binding
GO:0019899 enzyme binding
GO:0046872 metal ion binding
Biological Process
GO:0006468 protein phosphorylation
GO:0010744 positive regulation of macrophage derived foam cell differentiation
GO:0016310 phosphorylation
GO:0030154 cell differentiation
GO:0034351 negative regulation of glial cell apoptotic process
GO:0035556 intracellular signal transduction
GO:0045618 positive regulation of keratinocyte differentiation
GO:0050861 positive regulation of B cell receptor signaling pathway
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0060252 positive regulation of glial cell proliferation
GO:2000810 regulation of tight junction assembly
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000008 C2 domain
IPR000719 Protein kinase domain
IPR000961 AGC-kinase, C-terminal
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR014376 Protein kinase C, delta/epsilon/eta/theta types
IPR017892 Protein kinase, C-terminal
IPR020454 Diacylglycerol/phorbol-ester binding
IPR020635 Tyrosine-protein kinase, catalytic domain
PFAM PF00168
PF00069
PF07714
PF00130
PF00433
PRINTS PR00360
PR00109
PR00008
PIRSF PIRSF000551
SMART SM00239
SM00133
SM00109
SM00220
SM00219
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MY82
UniProt Splice Variant
Entrez Gene 518542
UniGene Bt.22013
RefSeq NP_001070331
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02029316 DAAA02029317 DAAA02029318 DAAA02029319
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca