Version 5.4
Bos taurus Protein: MAPRE2
Summary
InnateDB Protein IDBP-696238.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MAPRE2
Protein Name Microtubule-associated protein RP/EB family member 2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000009897
InnateDB Gene IDBG-643665 (MAPRE2)
Protein Structure
UniProt Annotation
Function May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Associated with the microtubule network. Accumulates at the plus end of microtubules (By similarity). {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008017 microtubule binding
Biological Process
GO:0007049 cell cycle
GO:0007067 mitotic nuclear division
GO:0051301 cell division
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005874 microtubule
GO:0015630 microtubule cytoskeleton
GO:0035371 microtubule plus-end
Protein Structure and Domains
PDB ID
InterPro IPR001715 Calponin homology domain
IPR004953 EB1, C-terminal
PFAM PF00307
PF03271
PRINTS
PIRSF
SMART SM00033
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3SZP2
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 510159
UniGene Bt.111444
RefSeq NP_001029546
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102764
GenPept AAI02765

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca