Version 5.4
Bos taurus Protein: ARAP2
Summary
InnateDB Protein IDBP-693924.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARAP2
Protein Name ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000044378
InnateDB Gene IDBG-641526 (ARAP2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
GO:0005515 protein binding
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0008060 ARF GTPase activator activity
GO:0008270 zinc ion binding
Biological Process
GO:0007165 signal transduction
GO:0032312 regulation of ARF GTPase activity
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0005622 intracellular
Protein Structure and Domains
PDB ID
InterPro IPR000159 Ras-association
IPR000198 Rho GTPase-activating protein domain
IPR001164 Arf GTPase activating protein
IPR001660 Sterile alpha motif domain
IPR001849 Pleckstrin homology domain
IPR008936 Rho GTPase activation protein
IPR011510 Sterile alpha motif, type 2
IPR013761 Sterile alpha motif/pointed domain
IPR021129 Sterile alpha motif, type 1
PFAM PF00788
PF00620
PF01412
PF00169
PF07647
PF00536
PRINTS PR00405
PIRSF
SMART SM00314
SM00324
SM00105
SM00454
SM00233
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MTN6
UniProt Splice Variant
Entrez Gene
UniGene Bt.63238
RefSeq
HUGO HGNC:16924
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02017407 DAAA02017408 DAAA02017409 DAAA02017410
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca