Version 5.4
Homo sapiens Protein: RASGRP1
Summary
InnateDB Protein IDBP-588804.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RASGRP1
Protein Name RAS guanyl releasing protein 1 (calcium and DAG-regulated)
Synonyms CALDAG-GEFI; CALDAG-GEFII; hRasGRP1; RASGRP; V;
Species Homo sapiens
Ensembl Protein ENSP00000454005
InnateDB Gene IDBG-5885 (RASGRP1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005085 guanyl-nucleotide exchange factor activity
Biological Process
GO:0051056 regulation of small GTPase mediated signal transduction
Cellular Component
GO:0005622 intracellular
Protein Structure and Domains
PDB ID
InterPro IPR000651 Ras-like guanine nucleotide exchange factor, N-terminal
PFAM PF00618
PRINTS
PIRSF
SMART SM00229
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H0YNG8
UniProt Splice Variant
Entrez Gene 10125
UniGene Hs.591127
RefSeq
HUGO HGNC:9878
OMIM 603962
CCDS
HPRD 04909
IMGT
EMBL AC116158 AC124306
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca