InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Synj1

Summary

InnateDB Protein

IDBP-400885.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Synj1

Protein Name

synaptojanin 1

Synonyms

A930006D20Rik; AA675315; mKIAA0910;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000113308

InnateDB Gene

IDBG-175516 (Synj1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	17 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
GO:0005515	protein binding
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity
GO:0042578	phosphoric ester hydrolase activity

Biological Process

GO:0006836	neurotransmitter transport
GO:0007612	learning
GO:0016082	synaptic vesicle priming
GO:0016191	synaptic vesicle uncoating
GO:0046488	phosphatidylinositol metabolic process
GO:0046855	inositol phosphate dephosphorylation
GO:0046856	phosphatidylinositol dephosphorylation
GO:0048015	phosphatidylinositol-mediated signaling
GO:0048488	synaptic vesicle endocytosis
GO:0048489	synaptic vesicle transport

Cellular Component

GO:0030117	membrane coat
GO:0030118	clathrin coat

Protein Structure and Domains

PDB ID

MGI:1354961

InterPro

IPR000300 Inositol polyphosphate-related phosphatase
IPR000504 RNA recognition motif domain
IPR002013 Synaptojanin, N-terminal
IPR005135 Endonuclease/exonuclease/phosphatase
IPR015047 Domain of unknown function DUF1866

PFAM

PF00076
PF02383
PF03372
PF14529
PF08952

PRINTS

PIRSF

SMART

SM00128
SM00360

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite