InnateDB Protein
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IDBP-362049.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SEPT5
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Protein Name
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septin 5
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Synonyms
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CDCREL; CDCREL-1; CDCREL1; H5; HCDCREL-1; PNUTL1;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000391311
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InnateDB Gene
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IDBG-1395 (SEPT5)
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Protein Structure
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Function |
Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in platelet secretion (By similarity). {ECO:0000250, ECO:0000305}.
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Subcellular Localization |
Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=In platelets, found in areas surrounding alpha-granules.
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Disease Associations |
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Tissue Specificity |
Expressed at high levels in the CNS, as well as in heart and platelets (at protein level). {ECO:0000269PubMed:12023038, ECO:0000269PubMed:15915442}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated |
Total |
26
[view]
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Protein-Protein |
26
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
2 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000038
Cell division protein GTP binding
IPR016491
Septin
IPR027417
P-loop containing nucleoside triphosphate hydrolase
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PFAM |
PF00735
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PRINTS |
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PIRSF |
PIRSF006698
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q99719
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PhosphoSite |
PhosphoSite-Q99719
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TrEMBL |
X5DNA9
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UniProt Splice Variant |
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Entrez Gene |
5413
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UniGene |
Hs.728762
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RefSeq |
NP_002679
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HUGO |
HGNC:9164
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OMIM |
602724
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CCDS |
CCDS13764
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HPRD |
04100
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IMGT |
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EMBL |
AC000093
AF006988
AK056273
AK295940
BC025261
CH471176
CR456545
KJ534756
U74628
Y11593
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GenPept |
AAB93438
AAC39779
AAH25261
AHW56396
BAB71133
BAG58724
CAA72332
CAG30431
EAX03027
EAX03030
EAX03031
EAX03032
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