InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SNX18

Summary

InnateDB Protein

IDBP-35227.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SNX18

Protein Name

sorting nexin 18

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000342276

InnateDB Gene

IDBG-20654 (SNX18)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.

Experimentally validated
Total	12 [view]
Protein-Protein	12 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
GO:0035091	phosphatidylinositol binding

Biological Process

GO:0000281	mitotic cytokinesis
GO:0006886	intracellular protein transport
GO:0006897	endocytosis
GO:0007067	mitotic nuclear division
GO:0015031	protein transport
GO:0016197	endosomal transport
GO:0036089	cleavage furrow formation
GO:0043547	positive regulation of GTPase activity

Cellular Component

GO:0005768	endosome
GO:0010008	endosome membrane
GO:0016023	cytoplasmic membrane-bounded vesicle
GO:0030136	clathrin-coated vesicle
GO:0030659	cytoplasmic vesicle membrane
GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR001452 SH3 domain
IPR001683 Phox homologous domain
IPR011511 Variant SH3 domain
IPR014536 Sorting nexin 9 subfamily
IPR019497 Sorting nexin protein, WASP-binding domain

PFAM

PF00018
PF14604
PF00787
PF07653
PF10456

PRINTS

PR00452

PIRSF

PIRSF027744

SMART

SM00326
SM00312

TIGRFAMs

Post-translational Modifications

Modification

Cross-References