Version 5.4
Homo sapiens Protein: CHEK2
Summary
InnateDB Protein IDBP-3326.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CHEK2
Protein Name CHK2 checkpoint homolog (S. pombe)
Synonyms CDS1; CHK2; hCds1; HuCds1; LFS2; PP1425; RAD53;
Species Homo sapiens
Ensembl Protein ENSP00000372006
InnateDB Gene IDBG-3314 (CHEK2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 109 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 109 [view]
Protein-Protein 103 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 3 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000253 Forkhead-associated (FHA) domain
IPR008984 SMAD/FHA domain
PFAM PF00498
PRINTS
PIRSF
SMART SM00240
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E7EPP1
UniProt Splice Variant
Entrez Gene 11200
UniGene Hs.505297
RefSeq
HUGO HGNC:16627
OMIM 604373
CCDS
HPRD 05084
IMGT
EMBL AL117330 AL121825
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca