Version 5.4
Homo sapiens Protein: TRIOBP
Summary
InnateDB Protein IDBP-293753.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRIOBP
Protein Name TRIO and F-actin binding protein
Synonyms DFNB28; dJ37E16.4; TAP68; TARA;
Species Homo sapiens
Ensembl Protein ENSP00000383913
InnateDB Gene IDBG-6969 (TRIOBP)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0017049 GTP-Rho binding
GO:0031625 ubiquitin protein ligase binding
GO:0045159 myosin II binding
GO:0051015 actin filament binding
Biological Process
GO:0007067 mitotic nuclear division
GO:0030047 actin modification
GO:0051016 barbed-end actin filament capping
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005815 microtubule organizing center
GO:0015629 actin cytoskeleton
GO:0030496 midbody
Protein Structure and Domains
PDB ID
InterPro IPR001849 Pleckstrin homology domain
PFAM PF00169
PRINTS
PIRSF
SMART SM00233
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H2D6
PhosphoSite PhosphoSite-Q9H2D6
TrEMBL F6WYE2
UniProt Splice Variant
Entrez Gene 11078
UniGene Hs.734724
RefSeq NP_619538
HUGO HGNC:17009
OMIM 609761
CCDS CCDS33644
HPRD 11028
IMGT
EMBL AB015343 AB051449 AF281030 BC003618 BC004303 BC013278 BC022200 DQ228003 DQ228004 DQ228005 DQ278603 Z83844
GenPept AAG44841 AAH03618 AAH04303 AAH13278 ABB59559 ABB59560 ABB59561 ABB77204 BAA34800 BAB33332

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca