InnateDB Protein
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IDBP-231428.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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THAP7
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Protein Name
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THAP domain containing 7
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000382084
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InnateDB Gene
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IDBG-1876 (THAP7)
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Protein Structure
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Function |
Chromatin-associated, histone tail-binding protein that represses transcription via recruitment of HDAC3 and nuclear hormone receptor corepressors. {ECO:0000269PubMed:15561719}.
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Subcellular Localization |
Nucleus. Chromosome.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
24
[view]
|
Protein-Protein |
24
[view]
|
Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
GO:0006351
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transcription, DNA-templated
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GO:0045892
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negative regulation of transcription, DNA-templated
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Cellular Component |
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PDB ID |
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InterPro |
IPR006612
Zinc finger, C2CH-type
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PFAM |
PF05485
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PRINTS |
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PIRSF |
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SMART |
SM00692
SM00980
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TIGRFAMs |
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Modification |
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SwissProt |
Q9BT49
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PhosphoSite |
PhosphoSite-Q9BT49
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
80764
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UniGene |
Hs.512756
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RefSeq |
NP_001008695
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HUGO |
HGNC:23190
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OMIM |
609518
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CCDS |
CCDS13787
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HPRD |
15500
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IMGT |
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EMBL |
AC002472
AK315457
BC004346
CH471176
CR456343
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GenPept |
AAH04346
BAG37844
CAG30229
EAX02919
EAX02921
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