InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Wnt9b

Summary

InnateDB Protein

IDBP-213054.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Wnt9b

Protein Name

wingless-type MMTV integration site 9B

Synonyms

clf; clf1; wnt-14b; wnt-15; Wnt14b; Wnt15;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000018630

InnateDB Gene

IDBG-213052 (Wnt9b)

Protein Structure

UniProt Annotation

Function

Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity). {ECO:0000250}.

Subcellular Localization

Secreted, extracellular space, extracellular matrix.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005102	receptor binding
GO:0005109	frizzled binding

Biological Process

GO:0001658	branching involved in ureteric bud morphogenesis
GO:0001701	in utero embryonic development
GO:0001822	kidney development
GO:0001932	regulation of protein phosphorylation
GO:0003339	regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0007165	signal transduction
GO:0007267	cell-cell signaling
GO:0007275	multicellular organismal development
GO:0009267	cellular response to starvation
GO:0009786	regulation of asymmetric cell division
GO:0009887	organ morphogenesis
GO:0016055	Wnt signaling pathway
GO:0030182	neuron differentiation
GO:0030539	male genitalia development
GO:0035150	regulation of tube size
GO:0043085	positive regulation of catalytic activity
GO:0045165	cell fate commitment
GO:0048701	embryonic cranial skeleton morphogenesis
GO:0048754	branching morphogenesis of an epithelial tube
GO:0060021	palate development
GO:0060070	canonical Wnt signaling pathway
GO:0060071	Wnt signaling pathway, planar cell polarity pathway
GO:0060993	kidney morphogenesis
GO:0061038	uterus morphogenesis
GO:0072003	kidney rudiment formation
GO:0072038	mesenchymal stem cell maintenance involved in nephron morphogenesis
GO:0072044	collecting duct development
GO:0072046	establishment of planar polarity involved in nephron morphogenesis
GO:0072078	nephron tubule morphogenesis
GO:0072164	mesonephric tubule development
GO:0072170	metanephric tubule development
GO:0072174	metanephric tubule formation
GO:0072181	mesonephric duct formation