InnateDB Protein
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IDBP-20470.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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NOA1
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Protein Name
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chromosome 4 open reading frame 14
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000264230
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InnateDB Gene
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IDBG-20466 (NOA1)
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Protein Structure
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Function |
Involved in regulation of mitochondrial protein translation and respiration. Plays a role in mitochondria-mediated cell death. May act as a scaffolding protein or stabilizer of respiratory chain supercomplexes. Binds GTP. {ECO:0000269PubMed:19103604}.
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Subcellular Localization |
Mitochondrion inner membrane {ECO:0000269PubMed:19103604}; Peripheral membrane protein {ECO:0000269PubMed:19103604}; Matrix side {ECO:0000269PubMed:19103604}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
13
[view]
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Protein-Protein |
13
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR027417
P-loop containing nucleoside triphosphate hydrolase
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8NC60
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PhosphoSite |
PhosphoSite-Q8NC60
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
84273
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UniGene |
Hs.8715
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RefSeq |
NP_115689
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HUGO |
HGNC:28473
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OMIM |
614919
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CCDS |
CCDS3510
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HPRD |
12823
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IMGT |
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EMBL |
AK074953
AK098215
BC004894
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GenPept |
AAH04894
BAC05262
BAC11311
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