InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Itpka

Summary

InnateDB Protein

IDBP-199877.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Itpka

Protein Name

inositol 1,4,5-trisphosphate 3-kinase A

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000028758

InnateDB Gene

IDBG-199875 (Itpka)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	1 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004683	calmodulin-dependent protein kinase activity
GO:0005516	calmodulin binding
GO:0005524	ATP binding
GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity
GO:0048365	Rac GTPase binding

Biological Process

GO:0006020	inositol metabolic process
GO:0006468	protein phosphorylation
GO:0030036	actin cytoskeleton organization
GO:0048167	regulation of synaptic plasticity
GO:0061003	positive regulation of dendritic spine morphogenesis
GO:0097062	dendritic spine maintenance