InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: C1qbp

Summary

InnateDB Protein

IDBP-195772.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

C1qbp

Protein Name

complement component 1, q subcomponent binding protein

Synonyms

AA407365; AA986492; D11Wsu182e; gC1qBP; HABP1; P32;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000077612

InnateDB Gene

IDBG-195770 (C1qbp)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 114 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	114 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001849	complement component C1q binding
GO:0003714	transcription corepressor activity
GO:0005080	protein kinase C binding
GO:0005515	protein binding
GO:0005540	hyaluronic acid binding
GO:0008134	transcription factor binding
GO:0030984	kininogen binding
GO:0031690	adrenergic receptor binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0014065	phosphatidylinositol 3-kinase signaling
GO:0030449	regulation of complement activation
GO:0032689	negative regulation of interferon-gamma production
GO:0032695	negative regulation of interleukin-12 production
GO:0039534	negative regulation of MDA-5 signaling pathway
GO:0039536	negative regulation of RIG-I signaling pathway
GO:0042256	mature ribosome assembly
GO:0043065	positive regulation of apoptotic process
GO:0045785	positive regulation of cell adhesion
GO:0048025	negative regulation of mRNA splicing, via spliceosome
GO:0050687	negative regulation of defense response to virus
GO:0051897	positive regulation of protein kinase B signaling
GO:0090023	positive regulation of neutrophil chemotaxis
GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
GO:1901165	positive regulation of trophoblast cell migration
GO:2000510	positive regulation of dendritic cell chemotaxis

Cellular Component

GO:0005615	extracellular space
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005759	mitochondrial matrix
GO:0005829	cytosol
GO:0009986	cell surface
GO:0016020	membrane