Version 5.4
Mus musculus Protein: 9630033F20Rik
Summary
InnateDB Protein IDBP-190569.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol 9630033F20Rik
Protein Name RIKEN cDNA 9630033F20 gene
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000048643
InnateDB Gene IDBG-190567 (9630033F20Rik)
Protein Structure
UniProt Annotation
Function Fructose-bisphosphatase hydrolyzing fructose-2,6- bisphosphate as well as fructose-1,6-bisphosphate. Inhibits glycolysis by reducing cellular levels of fructose-2,6- bisphosphate. May protect cells against reactive oxygen species and against apoptosis induced by tp53 (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity
Biological Process
GO:0009410 response to xenobiotic stimulus
GO:0010332 response to gamma radiation
GO:0010666 positive regulation of cardiac muscle cell apoptotic process
GO:0016311 dephosphorylation
GO:0060576 intestinal epithelial cell development
GO:1901525 negative regulation of macromitophagy
GO:2000378 negative regulation of reactive oxygen species metabolic process
Cellular Component
GO:0005622 intracellular
Protein Structure and Domains
PDB ID MGI:2442752
InterPro IPR013078 Histidine phosphatase superfamily, clade-1
IPR029033 Histidine phosphatase superfamily
PFAM PF00300
PRINTS
PIRSF
SMART SM00855
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BZA9
PhosphoSite PhosphoSite-Q8BZA9
TrEMBL B2RWB7
UniProt Splice Variant
Entrez Gene 319801
UniGene Mm.101836
RefSeq NP_795977
MGI ID
MGI Symbol 9630033F20Rik
OMIM
CCDS CCDS20563
HPRD
IMGT
EMBL AK036082 AK145896 AK163290 BC147705 BC147718 CH466523
GenPept AAI47706 AAI47719 BAC29298 BAE26732 BAE37278 EDK99854

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca