Version 5.4
Mus musculus Protein: Serpinb12
Summary
InnateDB Protein IDBP-185888.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Serpinb12
Protein Name serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 12
Synonyms 2300003F07Rik; 4833409F13Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000080030
InnateDB Gene IDBG-185886 (Serpinb12)
Protein Structure
UniProt Annotation
Function Inhibits trypsin and plasmin, but not thrombin, coagulation factor Xa, or urokinase-type plasminogen activator. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
Biological Process
GO:0002244 hematopoietic progenitor cell differentiation
GO:0010951 negative regulation of endopeptidase activity
GO:0030162 regulation of proteolysis
Cellular Component
GO:0005575 cellular_component
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:1919119
InterPro IPR023796 Serpin domain
PFAM PF00079
PRINTS
PIRSF
SMART SM00093
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9D7P9
PhosphoSite PhosphoSite-Q9D7P9
TrEMBL
UniProt Splice Variant
Entrez Gene 71869
UniGene Mm.321740
RefSeq NP_082247
MGI ID
MGI Symbol Serpinb12
OMIM
CCDS CCDS15212
HPRD
IMGT
EMBL AK009018 AK040697 AY367773 BC062134
GenPept AAH62134 AAR89287 BAB26028 BAC30672

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca