InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Sept3

Summary

InnateDB Protein

IDBP-166551.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Sept3

Protein Name

septin 3

Synonyms

3110018K01Rik; AV154067; B530002E20Rik; Sep3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000023095

InnateDB Gene

IDBG-166549 (Sept3)

Protein Structure

UniProt Annotation

Function

Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). {ECO:0000250, ECO:0000305}.

Subcellular Localization

Cytoplasm. Cytoplasm, cytoskeleton {ECO:0000250}. Cell junction, synapse {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0005525	GTP binding

Biological Process

GO:0007049	cell cycle
GO:0051301	cell division

Cellular Component

GO:0030054	cell junction
GO:0031105	septin complex
GO:0045202	synapse

Protein Structure and Domains

PDB ID

MGI:1345148

InterPro

IPR000038 Cell division protein GTP binding
IPR004881 Ribosome biogenesis GTPase RsgA, putative
IPR006703 AIG1
IPR008114 Septin 3
IPR016491 Septin
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00735
PF03193
PF04548

PRINTS

PR01741

PIRSF

PIRSF006698

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt