InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RANBP1

Summary

InnateDB Protein

IDBP-1623.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RANBP1

Protein Name

RAN binding protein 1

Synonyms

HTF9A;

Species

Homo sapiens

Ensembl Protein

ENSP00000327583

InnateDB Gene

IDBG-1621 (RANBP1)

Protein Structure

UniProt Annotation

Function

Inhibits GTP exchange on Ran. Forms a Ran-GTP-RANBP1 trimeric complex. Increase GTP hydrolysis induced by the Ran GTPase activating protein RANGAP1. May act in an intracellular signaling pathway which may control the progression through the cell cycle by regulating the transport of protein and nucleic acids across the nuclear membrane.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 28 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	28 [view]
Protein-Protein	28 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005092	GDP-dissociation inhibitor activity
GO:0005096	GTPase activator activity
GO:0008536	Ran GTPase binding

Biological Process

GO:0007165	signal transduction
GO:0016032	viral process
GO:0043547	positive regulation of GTPase activity
GO:0046907	intracellular transport
GO:0050790	regulation of catalytic activity