Version 5.4
Mus musculus Protein: Pard6g
Summary
InnateDB Protein IDBP-161042.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pard6g
Protein Name par-6 partitioning defective 6 homolog gamma (C. elegans)
Synonyms 2410049N21Rik; Par6a;
Species Mus musculus
Ensembl Protein ENSMUSP00000069182
InnateDB Gene IDBG-161040 (Pard6g)
Protein Structure
UniProt Annotation
Function Adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions. The PARD6-PARD3 complex links GTP- bound Rho small GTPases to atypical protein kinase C proteins (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm. Cell membrane {ECO:0000250}. Cell junction, tight junction {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 23 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007049 cell cycle
GO:0051301 cell division
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005923 tight junction
GO:0043234 protein complex
Protein Structure and Domains
PDB ID MGI:2135606
InterPro IPR000270 Phox/Bem1p
IPR001478 PDZ domain
PFAM PF00564
PF00595
PF13180
PRINTS
PIRSF
SMART SM00666
SM00228
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9JK84
PhosphoSite PhosphoSite-Q9JK84
TrEMBL Q8CBL3
UniProt Splice Variant
Entrez Gene 93737
UniGene Mm.407961
RefSeq NP_444347
MGI ID
MGI Symbol Pard6g
OMIM
CCDS CCDS29363
HPRD
IMGT
EMBL AF252290 AK035811
GenPept AAF71527 BAC29195

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca