InnateDB Protein
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IDBP-15670.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ADCY1
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Protein Name
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adenylate cyclase 1 (brain)
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Synonyms
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AC1; DFNB44;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000297323
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InnateDB Gene
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IDBG-15668 (ADCY1)
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Protein Structure
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Function |
This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina (By similarity). {ECO:0000250}.
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Subcellular Localization |
Membrane; Multi-pass membrane protein.
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Disease Associations |
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Tissue Specificity |
Brain, retina and adrenal medulla.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001054
Adenylyl cyclase class-3/4/guanylyl cyclase
IPR029787
Nucleotide cyclase
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PFAM |
PF00211
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PRINTS |
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PIRSF |
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SMART |
SM00044
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TIGRFAMs |
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Modification |
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SwissProt |
Q08828
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PhosphoSite |
PhosphoSite-Q08828
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TrEMBL |
Q8NFM5
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UniProt Splice Variant |
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Entrez Gene |
107
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UniGene |
Hs.192215
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RefSeq |
NP_066939
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HUGO |
HGNC:232
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OMIM |
103072
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CCDS |
CCDS34631
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HPRD |
00053
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IMGT |
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EMBL |
AC069008
AC091439
AF497515
CH236960
CH471128
L05500
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GenPept |
AAA02907
AAM94372
AAS07467
EAL23741
EAW61043
EAW61045
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