InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PITPNA

Summary

InnateDB Protein

IDBP-14962.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PITPNA

Protein Name

phosphatidylinositol transfer protein, alpha

Synonyms

HEL-S-36; PI-TPalpha; PITPN; VIB1A;

Species

Homo sapiens

Ensembl Protein

ENSP00000316809

InnateDB Gene

IDBG-14960 (PITPNA)

Protein Structure

UniProt Annotation

Function

Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes.

Subcellular Localization

Cytoplasm.

Disease Associations

Tissue Specificity

Expressed in a wide range of tissues.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008289	lipid binding
GO:0008525	phosphatidylcholine transporter activity
GO:0008526	phosphatidylinositol transporter activity

Biological Process

GO:0006629	lipid metabolic process
GO:0006810	transport
GO:0007411	axon guidance
GO:0007601	visual perception
GO:0015914	phospholipid transport

Cellular Component

GO:0005622	intracellular
GO:0005737	cytoplasm
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR001666 Phosphatidylinositol transfer protein

PFAM

PF02121

PRINTS

PR00391

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q00169

PhosphoSite

PhosphoSite-Q00169

TrEMBL

V9HWC5

UniProt Splice Variant

Entrez Gene

5306

UniGene

Hs.429819

RefSeq

NP_006215

HUGO

HGNC:9001

OMIM

600174

CCDS

CCDS45563

HPRD

02548

IMGT

EMBL

AC100748 AK303986 BC045108 BC082976 D30036 EU794647 M73704

GenPept

AAA36441 AAH45108 AAH82976 ACJ13701 BAA06276 BAG64903