InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Sept5

Summary

InnateDB Protein

IDBP-142048.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Sept5

Protein Name

septin 5

Synonyms

Cdcrel-1; Cdcrel1; Pnutl1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000094750

InnateDB Gene

IDBG-142046 (Sept5)

Protein Structure

UniProt Annotation

Function

Filament-forming cytoskeletal GTPase (By similarity). Involved in cytokinesis (Potential). May play a role in platelet secretion. {ECO:0000250, ECO:0000269PubMed:11880646, ECO:0000305}.

Subcellular Localization

Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.

Experimentally validated
Total	9 [view]
Protein-Protein	9 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	17 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005525	GTP binding

Biological Process

GO:0007049	cell cycle
GO:0017157	regulation of exocytosis
GO:0051301	cell division

Cellular Component

GO:0005886	plasma membrane
GO:0005938	cell cortex
GO:0008021	synaptic vesicle
GO:0031105	septin complex
GO:0043195	terminal bouton
GO:0043679	axon terminus
GO:0045202	synapse