InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Carhsp1

Summary

InnateDB Protein

IDBP-131824.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Carhsp1

Protein Name

calcium regulated heat stable protein 1

Synonyms

1200011K09Rik; Crhsp-24; D16Ertd465e;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000008537

InnateDB Gene

IDBG-131822 (Carhsp1)

Protein Structure

UniProt Annotation

Function

Binds mRNA and regulates the stability of target mRNA. {ECO:0000269PubMed:21078874}.

Subcellular Localization

Cytoplasm {ECO:0000269PubMed:21078874}. Cytoplasm, P-body {ECO:0000269PubMed:21078874}. Cytoplasmic granule {ECO:0000269PubMed:21078874}. Note=Detected at cytoplasmic stress granules and P-bodies. Detected at exosome granules where mRNA is degraded.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Experimentally validated
Total	11 [view]
Protein-Protein	10 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0003730	mRNA 3'-UTR binding
GO:0005515	protein binding

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0043488	regulation of mRNA stability

Cellular Component

GO:0000177	cytoplasmic exosome (RNase complex)
GO:0000932	cytoplasmic mRNA processing body
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0043186	P granule
GO:0070062	extracellular vesicular exosome