Version 5.4
Mus musculus Protein: Mapre2
Summary
InnateDB Protein IDBP-131278.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mapre2
Protein Name microtubule-associated protein, RP/EB family, member 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000025127
InnateDB Gene IDBG-131276 (Mapre2)
Protein Structure
UniProt Annotation
Function May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Associated with the microtubule network. Accumulates at the plus end of microtubules (By similarity). {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008017 microtubule binding
Biological Process
GO:0007067 mitotic nuclear division
Cellular Component
GO:0005737 cytoplasm
GO:0015630 microtubule cytoskeleton
GO:0035371 microtubule plus-end
Protein Structure and Domains
PDB ID MGI:106271
InterPro IPR001715 Calponin homology domain
IPR004953 EB1, C-terminal
PFAM PF00307
PF03271
PRINTS
PIRSF
SMART SM00033
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8R001
PhosphoSite PhosphoSite-Q8R001
TrEMBL E9Q6X0
UniProt Splice Variant
Entrez Gene 212307
UniGene Mm.488872
RefSeq NP_694698
MGI ID
MGI Symbol Mapre2
OMIM
CCDS CCDS29095
HPRD
IMGT
EMBL AC132419 AC145084 AK028823 AK038562 AK040767 AK045493 AK045904 AK046221 AK148954 BC025804 BC027056 BC028987 BC035254
GenPept AAH25804 AAH27056 AAH28987 AAH35254 BAC26138 BAC30045 BAC30700 BAC32393 BAC32643 BAE28700 BAE43326

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca