Version 5.4
Homo sapiens Gene: FERMT2
Summary
InnateDB Gene IDBG-6911.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FERMT2
Gene Name fermitin family member 2
Synonyms KIND2; mig-2; MIG2; PLEKHC1; UNC112; UNC112B
Species Homo sapiens
Ensembl Gene ENSG00000073712
Encoded Proteins
IDBP-6913
fermitin family member 2
IDBP-6915
fermitin family member 2
IDBP-230928
fermitin family member 2
IDBP-239140
fermitin family member 2
IDBP-588483
fermitin family member 2
IDBP-595729
fermitin family member 2
IDBP-596848
fermitin family member 2
IDBP-589525
fermitin family member 2
IDBP-603185
fermitin family member 2
IDBP-588807
fermitin family member 2
IDBP-584132
fermitin family member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 14:52857268-52952435
Strand Reverse strand
Band q22.1
Transcripts
ENST00000341590 ENSP00000340391
ENST00000343279 ENSP00000342858
ENST00000399304 ENSP00000382243
ENST00000395631 ENSP00000378993
ENST00000557255
ENST00000554152 ENSP00000450741
ENST00000555546
ENST00000553373 ENSP00000451084
ENST00000553663 ENSP00000451134
ENST00000553768
ENST00000554288 ENSP00000451268
ENST00000555692 ENSP00000452472
ENST00000554712 ENSP00000450506
ENST00000557562 ENSP00000451085
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 44 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 44 [view]
Protein-Protein 44 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
Biological Process
GO:0007160 cell-matrix adhesion
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0007229 integrin-mediated signaling pathway
GO:0008360 regulation of cell shape
GO:0016055 Wnt signaling pathway
GO:0033622 integrin activation
GO:0034329 cell junction assembly
GO:0034446 substrate adhesion-dependent cell spreading
GO:0048041 focal adhesion assembly
GO:0072657 protein localization to membrane
Cellular Component
GO:0001725 stress fiber
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005925 focal adhesion
GO:0005938 cell cortex
GO:0009986 cell surface
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
GO:0031258 lamellipodium membrane
GO:0031674 I band
GO:0031941 filamentous actin
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000037712
View Gene Order
ENSBTAG00000014501
Not yet available
Pathways
NETPATH
REACTOME
REACT_20649
Cell-extracellular matrix interactions pathway
REACT_111155
Cell-Cell communication pathway
REACT_20676
Cell junction organization pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.509343 Hs.710380 Hs.714524
RefSeq NM_001134999 NM_001135000 NM_006832 XM_005267285 XM_006720009
HUGO
OMIM
CCDS CCDS45107 CCDS45108 CCDS9713
HPRD 06374
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca