Version 5.4
Homo sapiens Gene: TMX1
Summary
InnateDB Gene IDBG-6529.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMX1
Gene Name thioredoxin-related transmembrane protein 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000139921
Encoded Proteins
IDBP-368643
thioredoxin-related transmembrane protein 1
IDBP-595312
thioredoxin-related transmembrane protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary TXNDC1 is a thioredoxin (TXN; see MIM 187700)-related protein with disulfide reductase activity (Matsuo et al., 2001 [PubMed 11152479]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:51240162-51257546
Strand Forward strand
Band q22.1
Transcripts
ENST00000457354 ENSP00000393316
ENST00000555574
ENST00000556683 ENSP00000451585
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
Experimentally validated
Total 18 [view]
Protein-Protein 18 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003756 protein disulfide isomerase activity
GO:0015036 disulfide oxidoreductase activity
Biological Process
GO:0006457 protein folding
GO:0034976 response to endoplasmic reticulum stress
GO:0045454 cell redox homeostasis
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005730 nucleolus
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000021072
View Gene Order
ENSBTAG00000011225
Not yet available
Cross-References
SwissProt Q9H3N1
TrEMBL G3V448
UniProt Splice Variant
Entrez Gene 81542
UniGene Hs.125221 Hs.607313
RefSeq NM_030755
HUGO HGNC:15487
OMIM 610527
CCDS CCDS41953
HPRD
IMGT
EMBL AB048246 AK075395 AK312905 AL080080 AL591807 AY358640 BC036460 BC056874 CH471078
GenPept AAH36460 AAH56874 AAQ89003 BAB20629 BAC11593 BAG35751 CAB45700 EAW65678
RNA Seq Atlas 81542

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca